What is/are Zestoretic?

HYDROCHLOROTHIAZIDE; LISINOPRIL is a combination of a diuretic and an ACE inhibitor. It is used to treat high blood pressure. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

bone marrow disease decreased urine heart or blood vessel disease if you are on a special diet like a low salt diet immune system problems, like lupus kidney disease liver disease previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat recent heart attack or stroke an unusual or allergic reaction to lisinopril, hydrochlorothiazide, sulfa drugs, other medicines, insect venom, foods, dyes, or preservatives pregnant or trying to get pregnant breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You may take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

barbiturates like phenobarbital blood pressure medicines corticosteroids like prednisone diabetic medications diuretics, especially triamterene, spironolactone or amiloride lithium NSAIDs like ibuprofen potassium salts or potassium supplements prescription pain medicines skeletal muscle relaxants like tubocurarine some cholesterol lowering medications like cholestyramine or colestipol

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

confusion, dizziness, light headedness or fainting spells decreased amount of urine passed difficulty breathing or swallowing, hoarseness, or tightening of the throat fast or irregular heart beat, palpitations, or chest pain muscle cramps nausea and vomiting persistent dry cough redness, blistering, peeling or loosening of the skin, including inside the mouth stomach pain swelling of your face, lips, tongue, hands, or feet unusual rash, bleeding or bruising, or pinpoint red spots on the skin worsened gout pain yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

cough decreased sexual function or desire headache

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her. Call your doctor or health care professional if you notice an irregular or fast heart beat.

You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

This medicine may affect your blood sugar level. If you have diabetes, check with your doctor or health care professional before changing the dose of your diabetic medicine.

Avoid salt substitutes unless you are told otherwise by your doctor or health care professional.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and excessive light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

What is/are Vaseretic Tablets?

ENALAPRIL; HYDROCHLOROTHIAZIDE is a combination of of a diuretic and an ACE inhibitor. It is used to treat high blood pressure. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

bone marrow disease decreased urine heart or blood vessel disease if you are on a special diet, such as a low salt diet immune system disease, like lupus kidney disease liver disease low blood pressure previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat recent heart attack or stroke an unusual or allergic reaction to enalapril, hydrochlorothiazide, sulfa drugs, other medicines, insect venom, foods, dyes, or preservatives pregnant or trying to get pregnant breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You may take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following:

diazoxide

This medicine may also interact with the following:

barbiturates like phenobarbital blood pressure medicines corticosteroids like prednisone diabetic medications diuretics, especially triamterene, spironolactone or amiloride lithium medicines for high cholesterol like cholestyramine or colestipol NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen potassium supplements prescription pain medicines skeletal muscle relaxants like tubocurarine

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue breathing problems chest pain decreased amount of urine passed dry cough feeling faint or lightheaded, falls muscle cramps nausea and vomiting redness, blistering, peeling or loosening of the skin, including inside the mouth stomach pain unusual bleeding or bruising, or pinpoint red spots on the skin worsened gout pain yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

change in sex drive or performance cough headache

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her. Call your doctor or health care professional if you notice an irregular or fast heart beat.

You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

This medicine may affect your blood sugar level. If you have diabetes, check with your doctor or health care professional before changing the dose of your diabetic medicine.

Avoid salt substitutes unless you are told otherwise by your doctor or health care professional.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature below 30 degrees C (86 degrees F). Keep container tightly closed. Protect from moisture. Throw away any unused medicine after the expiration date.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Drug Name

Trandate (Labetalol)

Drug Uses

This medication is used to treat severe high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

How Taken

Follow the directions for using this medicine provided by your doctor. Take this medicine with food or milk.

Drug Class and Mechanism

Trandate is a drug that is used for treating high blood pressure. It is related to carvedilol (Coreg). Nerves that are part of the adrenergic nervous system travel to most arteries where they release an adrenergic chemical norepinephrine. The norepinephrine attaches to receptors on the muscles of the arteries and causes the muscles to contract, narrowing the arteries, and increasing the blood pressure. Trandate blocks receptors of the adrenergic nervous system. When trandate attaches to and blocks the receptors, the arterial muscles relax, and the arteries expand, resulting in a fall in blood pressure. The FDA first approved Trandate in 1997.

Missed Dose

If the dose is interrupted, contact the doctor immediately to re-establish dosing.

Storage

Store the vials at room temperature between 36 and 86 degrees F (2 to 30 degrees C) and away from light. Do not freeze. After dilution in the correct IV fluids, this product is stable for 24 hours refrigerated or at room temperature. Discard any unused liquid.

Warnings/Precautions

Tell your doctor your medical history, especially of: liver problems, heart problems (e.g., mild/moderate congestive heart failure), pheochromocytoma, diabetes, any allergies. This medication is not recommended for use if you have the following medical conditions: lung disease (asthma, COPD), certain heart problems (e.g. advanced heart block, severe bradycardia, severe heart failure, post-CABG surgery).

This drug may make you dizzy for up to 3 hours after it is given. You should remain lying down during this time period in order to prevent falls. You should get up slowly when rising from a seated or lying position; another person should assist you. Use caution when performing activities that require alertness such as driving or using machinery.

Limit alcoholic beverages. If you have a history of severe allergic reactions, consult your doctor or pharmacist. Normal doses of epinephrine may not be as effective while you are using this medication. If you are diabetic, this drug may block certain symptoms of low blood sugar. Increased sweating is a symptom that is not affected.

Consult your doctor or pharmacist for more details. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. Trandate should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This medication passes into breast milk. Consult your doctor before breast-feeding.

Possible Side Effects

Fatigue, nausea, or tingling of the scalp/skin may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if this potentially serious side effect occurs: dizziness. Tell your doctor immediately if these unlikely but serious side effects occur: fainting, leg pain, increased sweating, increased urination, unusual thirst. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: unusually slow or irregular heartbeat, persistent loss of appetite, stomach pain, persistent sore throat or fever, easy bleeding or bruising, vision changes, difficulty urinating, mental/mood changes.

Rare, but possibly fatal, liver problems have occurred during labetalol use. Seek immediate medical attention if you develop: dark urine, yellowing eyes or skin. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.

Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.

If you notice other effects not listed above, call your doctor or pharmacist.

More Information

Laboratory and/or medical tests (e.g., liver function) may be performed to monitor your progress.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

What is/are Amiloride and Hydrochlorothiazide?

AMILORIDE; HYDROCHLOROTHIAZIDE is a combination of two types of diuretics. It helps you make more urine and to lose excess water from your body. This medicine is used to treat high blood pressure and heart failure. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

• diabetes
• immune system problems, like lupus
• kidney disease
• small amount of urine
• unusual or allergic reaction to amiloride, hydrochlorothiazide, other diuretics, sulfa drugs, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take it at regular intervals. Remember that you will need to pass urine frequently after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not take at bedtime. Do not take your medicine more often than directed. Do not stop taking except on your doctor’s advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following:

• eplerenone
• potassium sparing diuretics
• quinidine

This medicine may also interact with the following:

• ACE inhibitors for heart or kidney disease like captopril, lisinopril
• antiinflammatory drugs, NSAIDs like ibuprofen
• alcohol
• barbiturate medicines for sleep or seizure control
• cholestyramine, colestipol
• cyclosporine
• lithium
• medicines for diabetes
• medicines for high blood pressure or heart failure
• muscle relaxers
• neuromuscular blockers used during surgery
• other diuretics
• potassium supplements
• some medicines for pain like codeine
• steroid hormones like cortisone, hydrocortisone, prednisone
• tacrolimus

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• black or tarry stools
• breathing problems
• fast, irregular heartbeat
• feeling faint or lightheaded, falls
• fever
• muscle pain, cramps
• numbness, tingling in hands or feet
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• trouble passing urine or change in the amount of urine
• unusual bleeding
• unusually weak or tired
• worsened gout pain
• yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blurred vision
• change in sex drive or performance
• constipation
• dry mouth, increased thirst
• enlarged, tender breasts
• headache
• irregular menstrual periods
• stomach pain

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor what your blood pressure should be, and when you should contact them. If you are diabetic, check your blood sugar as directed.

You may need to be on a special diet while taking this medicine. Ask your doctor. You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Prazosin is used for:

Treating high blood pressure and benign prostatic hyperplasia (BPH). It may also be used to treat other conditions as determined by your doctor.

Prazosin is an alpha-blocker. The exact way it works is unknown, but it is thought to block a chemical in the body, causing blood vessels and the muscles around the urethra to relax. This helps to lower blood pressure and to improve urinary symptoms associated with enlargement of the prostate (BPH).

Do NOT use Prazosin if:

• you are allergic to any ingredient in Prazosin
• you are taking phosphodiesterase type 5 inhibitors (eg, vardenafil, tadalafil) or modafinil

Contact your doctor or health care provider right away if any of these apply to you.

Before using Prazosin :

Some medical conditions may interact with Prazosin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have chest pain, heart disease, narcolepsy, or kidney problems

Some MEDICINES MAY INTERACT with Prazosin. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Indomethacin because the effectiveness of Prazosin may be decreased
• Verapamil because the actions and side effects of Prazosin may be increased
• Beta-blockers (eg, propranolol), bupivacaine, nifedipine, or phosphodiesterase type 5 inhibitors (eg, sildenafil) because the actions and side effects of these medicines may be increased
• Modafinil because its effectiveness may be decreased by Prazosin

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prazosin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Prazosin :

Use Prazosin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Prazosin may be taken with or without food.
• If you miss a dose of Prazosin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Prazosin.

Important safety information:

• Prazosin may cause dizziness, lightheadedness, or fainting after the first dose. Take the first dose at bedtime. If you get up during the night, sit up and stand slowly. Continue to sit up and stand slowly while you are taking Prazosin.
• Prazosin may cause dizziness, drowsiness, lightheadedness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Prazosin. Using Prazosin alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Before drinking alcohol, discuss it with your doctor.
• Patients being treated for high blood pressure often feel tired and run down for a few weeks after beginning therapy. Continue taking your medicine even though you may not feel quite “normal.”
• Avoid engaging in any hazardous tasks for at least 24 hours after taking the first dose, missing several doses, increasing the dose, or taking other high blood pressure medications.
• Drinking alcohol, standing for long periods of time, exercising, and exposing yourself to hot weather can cause dizziness, lightheadedness, or fainting while you are taking Prazosin.
• Use Prazosin with extreme caution in the ELDERLY because they may be more sensitive to its effects.
• Prazosin is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Prazosin during pregnancy. This medicine is excreted in breast milk. If you are or will be breast-feeding, check with your doctor to discuss the risks to your baby.

Possible side effects of Prazosin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; depression; dizziness; drowsiness; dry mouth; feeling of a whirling motion; flushing; frequent urination; headache; lack of energy; lightheadedness; nasal congestion; nausea; nervousness; nosebleed; stuffy nose; swelling; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; fainting; pounding heartbeat; puffiness in hands or feet; rapid heartbeat.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Hydrochlorothiazide/Generic Microzide is used for:

Treating excess fluid buildup in the body caused by certain conditions or medicines. It may also be used to treat high blood pressure or other conditions as determined by your doctor.

Hydrochlorothiazide is a thiazide diuretic. It works by helping the kidneys eliminate fluid from your body. Exactly how Hydrochlorothiazide works to treat high blood pressure is unknown.

Do NOT use Hydrochlorothiazide if:

• you are allergic to any ingredient in Hydrochlorothiazide or to any other sulfonamide medicine (eg sulfamethoxazole, glyburide, acetazolamide)
• you are unable to urinate
• you are taking dofetilide or ketanserin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Hydrochlorothiazide :

Some medical conditions may interact with Hydrochlorothiazide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have gout, liver problems, lupus, kidney problems, diabetes, asthma, parathyroid problems, or high blood cholesterol or lipid levels
• if you have low blood sodium, chloride, potassium, or magnesium levels; or high blood calcium levels

Some MEDICINES MAY INTERACT with Hydrochlorothiazide. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Cholestyramine, colestipol, or nonsteroidal anti-inflammatory medicines (NSAIDs) (eg, ibuprofen) because they decrease the effectiveness of Hydrochlorothiazide
• Barbiturates (eg, phenobarbital), corticosteroids (eg, prednisone), narcotic pain medicines (eg, codeine, morphine, fentanyl), or medicines for high blood pressure because side effects of Hydrochlorothiazide may be increased
• Diazoxide or nondepolarizing muscle relaxants (eg, tubocurarine) because side effects may be increased by Hydrochlorothiazide
• Lithium because risk of toxicity may be increased by Hydrochlorothiazide
• Digoxin, dofetilide, or ketanserin because risk of irregular heartbeat may be increased by Hydrochlorothiazide
• Diabetes medicines (eg, glipizide, metformin), insulin, or pressor amines (eg, norepinephrine) because the effectiveness may be decreased by Hydrochlorothiazide

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hydrochlorothiazide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hydrochlorothiazide :

Use Hydrochlorothiazide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Hydrochlorothiazide may be taken with or without food.
• When you first start taking Hydrochlorothiazide , it may cause an increase in urine or in frequency of urination. To prevent this from affecting sleep, try not to take any dose later than 6 pm.
• If you miss a dose of Hydrochlorothiazide , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Hydrochlorothiazide.

Important safety information:

• Hydrochlorothiazide may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Hydrochlorothiazide. Using Hydrochlorothiazide alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Hydrochlorothiazide may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Hydrochlorothiazide.
• Hydrochlorothiazide may cause high blood sugar (eg, thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor). If these symptoms occur, tell your doctor immediately.
• Your doctor may have also prescribed a potassium supplement for you. If so, follow the dosing carefully. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor.
• Hydrochlorothiazide may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Hydrochlorothiazide. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medication even though you may not feel quite “normal.” Contact your doctor or pharmacist about any new symptoms.
• LAB TESTS, including kidney function, blood pressure, and blood electrolyte levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Use Hydrochlorothiazide with caution in the ELDERLY because they may be more sensitive to its effects.
• Hydrochlorothiazide is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Hydrochlorothiazide during pregnancy. Hydrochlorothiazide is excreted in breast milk. Do not breast-feed while taking Hydrochlorothiazide.

Possible side effects of Hydrochlorothiazide :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; diarrhea; dizziness; drowsiness; inability to keep an erection; lightheadedness especially when sitting up or standing; loss of appetite; nausea; rash or itching; redness of the skin; uncontrolled muscle movement.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; decrease in amount of urine; drowsiness; gout; inflammation of the pancreas; muscle pain or cramps; rapid or irregular heartbeat; restlessness; seizures; unusual thirst; unusual tiredness or weakness; unusually dry mouth; vomiting.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Drug Name

Micardis (Telmisartan)

Drug Uses

This drug is used to treat high blood pressure (hypertension). This drug works by blocking the hormone angiotensin thereby relaxing blood vessels, causing them to widen. High blood pressure reduction helps prevent strokes, heart attacks, and kidney problems.

How Taken

Take this medication by mouth, usually once daily or as directed by your doctor. You may take this drug with or without food. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can raise your potassium levels, which rarely can cause serious side effects such as muscle weakness or very slow heartbeats. Tell your doctor immediately if these effects occur. The dosage is based on your medical condition and response to therapy. For the treatment of high blood pressure, it may take 4 weeks before the full benefit of this drug occurs. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

Drug Class and Mechanism

Micardis is a member of a family of drugs called angiotensin receptor blockers (ARBs), which includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand). ARBs block the ability of the chemical angiotensin II to constrict or squeeze arteries and veins. As a result, the arteries and veins enlarge and blood pressure falls. The reduced pressure in the arteries also makes it easier for the heart to pump blood. Micardis was approved by the FDA in November of 2000.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature (77 degrees F or 25 degrees C) away from light. This drug is sensitive to moisture. Therefore keep each dose in the manufacturer’s original packaging until right before taking it. Brief storage between 59 and 86 degrees F (15 to 30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Warnings/Precautions

This drug can cause serious fetal harm (possibly death) if used during the last six months of pregnancy. If you become pregnant or think you may be pregnant, contact your doctor immediately. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood levels of potassium, heart problems, severe dehydration (and loss of electrolytes such as sodium), diabetes (poorly controlled), any allergies (especially to ACE inhibitors such as captopril, lisinopril).

This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position. Before having surgery, tell your doctor or dentist that you are taking this medication. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially the dizziness effect.

This medication should be used only when clearly needed during the first three months of pregnancy. It is not recommended for use during the last six months of the pregnancy due to the risk for fetal harm. Discuss the risks and benefits with your doctor. See also the Warning section. It is not known if this drug passes into breast milk. Breast-feeding is not recommended due to the potential harm to the nursing infant. Consult your doctor before breast-feeding.

Possible Side Effects

You may experience

• dizziness,
• lightheadedness,
• blurred vision,
• or back pain as your body adjusts to the medication.

If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

• fainting,
• decreased sexual ability.

Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: change in the amount of urine.

An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.

Symptoms of an allergic reaction include:

• rash,
• itching,
• swelling (especially of the face, lips, tongue, or throat),
• severe dizziness,
• trouble breathing.

If you notice other effects not listed above, contact your doctor or pharmacist.

More Information

Do not share this medication with others. Lifestyle changes such as stress reduction programs, exercise and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Laboratory and/or medical tests (e.g., kidney function, potassium blood level) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Have your blood pressure checked regularly while taking this medication. Learn how to monitor your own blood pressure at home. Discuss this with your doctor.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Indapamide is used for:

Treating high blood pressure, swelling, or congestive heart failure due to excess fluid in the body.

Indapamide is a diuretic. It works by causing the kidneys to eliminate large amounts of water and salts.

Do NOT use Indapamide if:

• you are allergic to any ingredient in Indapamide
• you are unable to urinate or have problems urinating
• you are taking ketanserin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Indapamide :

Some medical conditions may interact with Indapamide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart, liver or kidney disease, or have low levels of sodium or potassium in your body
• if you have gout or lupus

Some MEDICINES MAY INTERACT with Indapamide. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the effectiveness of Indapamide may be decreased
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), diazoxide, or ketanserin because the risk of kidney problems may be increased
• Allopurinol, amantadine, antineoplastic agents (eg, cyclophosphamide), digitalis glycosides (eg, digoxin), lithium, or nondepolarizing muscle relaxants (eg, vecuronium) because the actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Indapamide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Indapamide :

Use Indapamide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Indapamide may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• When you first start taking Indapamide , it may cause an increase in the amount of urine or in frequency of urination. To prevent this from affecting sleep, try not to take any dose later than 6 pm.
• If you miss a dose of Indapamide and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Indapamide.

Important safety information:

• Indapamide may cause drowsiness, dizziness, lightheadedness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Indapamide. Using Indapamide alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Indapamide may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit or stand up slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.
• Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medication even though you may not quite feel “normal.” Contact your doctor or pharmacist about new symptoms.
• Your doctor may have also prescribed a potassium supplement for you. If so, follow the dosing carefully. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor.
• Indapamide may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Indapamide. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Indapamide.
• Diabetes patients – Indapamide may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
• LAB TESTS, including electrolyte levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Indapamide during pregnancy. It is unknown if Indapamide is excreted in breast milk. Do not breast-feed while taking Indapamide.

Possible side effects of Indapamide :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness or lightheadedness when siting up or standing; headache; infection; nervousness; pain; runny nose; trouble sleeping; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; drowsiness; fatigue; irregular heartbeat; muscle cramps; numbness of your hands or feet; pounding in the chest; rapid heartbeat; unusual tiredness; urination problems; weakness; yellowing of the skin or eyes.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Drug Name

Lopid (Gemfibrozil)

Drug Uses

Lopid (also known as a fibrate medication) is used along with a proper diet to help lower fats (triglycerides) and cholesterol in the blood. This drug is usually prescribed after non-drug treatment options have not been fully successful at lowering cholesterol (e.g., diet change, increase in exercise, weight loss if overweight). This drug is thought to work by decreasing the amount of fat produced by the liver. Reducing cholesterol and triglycerides lowers the risk of heart disease and helps prevent strokes and heart attacks. This drug also helps to prevent pancreas disease (pancreatitis) in patients with very high blood levels of triglycerides.

How Taken

Take this medication by mouth usually twice a day, 30 minutes before your morning and evening meals, or as directed by your doctor. Dosage is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. It may take between 1-3 months before the full benefit of this drug takes effect. It is important to continue taking this medication even if you feel well. Most people with high triglycerides or cholesterol do not feel sick.

Drug Class and Mechanism

Lopid is a lipid- and cholesterol-modifying medicine. It reduces triglycerides and increases cholesterol carried in high density lipoprotein (HDL) in the blood. HDL cholesterol is sometimes called “good” cholesterol because higher concentrations of HDL cholesterol in the blood are associated with a reduced risk of heart disease. The decrease in triglycerides is thought to be due in part to reduced release of triglycerides from fat tissue in the body. In one large study, lopid decreased the risk of heart attacks but did not affect the overall survival of persons with high cholesterols.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store the US product at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Store the Canadian product at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Warnings/Precautions

Before taking lopid, tell your doctor or pharmacist if you are allergic to it, or if you have any other allergies. This medication should not be used if you have certain medical conditions.

Before using this medicine, consult your doctor or pharmacist if you have:

• liver disease (e.g., primary biliary cirrhosis),
• gallbladder disease,
• severe kidney disease.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• diabetes (poorly controlled),
• underactive thyroid (hypothyroidism),
• alcohol use.

The rare development of severe muscle damage (see Side Effects) can infrequently lead to serious kidney problems. This medication is usually stopped temporarily if you have any condition which can increase your risk of developing kidney problems.

Before stopping your medication, notify your doctor immediately if you have any of the following conditions:

• major surgery,
• trauma,
• serious illness (e.g., sepsis, severe metabolic/endocrine/electrolyte disorders),
• very low blood pressure,
• uncontrolled seizures.

This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

Possible Side Effects

Stomach/abdominal upset or pain, dizziness, drowsiness, unusual taste, numbness/tingling of hands/feet, or blurred vision may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Tell your doctor immediately if any of these serious side effects occur:

• decreased sexual desire or ability,
• depression.

Tell your doctor immediately if any of these highly unlikely but very serious side effects occur:

• signs of infection (e.g. fever, persistent sore throat),
• easy bruising/bleeding,
• unusual fatigue,
• irregular heartbeat.

This medication may infrequently cause muscle damage (which can rarely lead to a very serious, possibly fatal, condition called rhabdomyolysis).

Stop taking this drug and tell your doctor immediately if you develop:

• muscle pain/tenderness/weakness (especially with fever or unusual tiredness),
• unusual change in the amount of urine.

This drug may infrequently cause abdominal problems (e.g., gallstones, gallbladder disease requiring surgery).

Stop taking this drug and tell your doctor immediately if you develop:

• severe stomach/abdominal pain,
• persistent nausea/vomiting,
• yellowing eyes or skin,
• dark urine,
• unusual tiredness.

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

More Information

Do not share this medication with others. Laboratory and/or medical tests (e.g., blood triglyceride and cholesterol levels, liver function tests, complete blood count, fasting blood sugar levels or FBS) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. For best results this medication should be used along with exercise, a low-fat/low-cholesterol diet, and weight loss program if you are overweight. In addition, check your blood pressure regularly, seek medical treatment if your blood pressure is high, and stop smoking to further help reduce your risk for a heart attack or stroke. Consult your doctor for more details.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.