What is/are Hyzaar?

LOSARTAN; HYDROCHLOROTHIAZIDE is a combination of a drug that relaxes blood vessels and a diuretic. It is used to treat high blood pressure. This medicine may also reduce the risk of stroke in certain patients. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

• decreased urine
• kidney disease
• liver disease
• if you are on a special diet, like a low-salt diet
• immune system problems, like lupus
• an unusual or allergic reaction to losartan, hydrochlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. This medicine can be taken with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

• barbiturates, like phenobarbital
• blood pressure medicines
• celecoxib
• cimetidine
• corticosteroids
• diabetic medicines
• diuretics, especially triamterene, spironolactone or amiloride
• fluconazole
• lithium
• NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
• potassium salts or potassium supplements
• prescription pain medicines
• rifampin
• skeletal muscle relaxants like tubocurarine
• some cholesterol-lowering medicines like cholestyramine or colestipol

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• breathing problems
• dark urine
• fast or irregular heart beat, palpitations, or chest pain
• feeling faint or lightheaded
• muscle cramps
• persistent dry cough
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• stomach pain
• trouble passing urine or change in the amount of urine
• unusual bleeding or bruising
• worsened gout pain
• yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• change in sex drive or performance
• headache

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Check your blood pressure regularly while you are taking this medicine. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her. When you check your blood pressure, write down the measurements to show your doctor or health care professional. If you are taking this medicine for a long time, you must visit your health care professional for regular checks on your progress. Make sure you schedule appointments on a regular basis.

You must not get dehydrated. Ask your doctor or health care professional how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child, particularly in the second or third trimester. Talk to your health care professional or pharmacist for more information.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

This medicine may affect your blood sugar level. If you have diabetes, check with your doctor or health care professional before changing the dose of your diabetic medicine.

Avoid salt substitutes unless you are told otherwise by your doctor or health care professional.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Terazosin is used for:

Treating high blood pressure and treating signs and symptoms of benign prostatic hyperplasia (BPH).

Terazosin is an alpha-blocker. It works by relaxing muscles in the blood vessels, resulting in lowering of blood pressure. In BPH, alpha-blockers work by relaxing muscles around the urethra (tube that drains urine from the bladder), which improves urinary symptoms.

Do NOT use Terazosin if:

• you are allergic to any ingredient in Terazosin or to similar medicines (eg, prazosin)
• you are currently taking a phosphodiesterase type 5 inhibitor (eg, sildenafil), a medicine used frequently for sexual dysfunction

Contact your doctor or health care provider right away if any of these apply to you.

Before using Terazosin :

Some medical conditions may interact with Terazosin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have prostate cancer, angina pectoris, heart disease, kidney or liver problems, or any other medical condition

Some MEDICINES MAY INTERACT with Terazosin. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Phosphodiesterase type 5 inhibitors (eg, sildenafil) or verapamil because severe dizziness, lightheadedness, or fainting may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Terazosin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Terazosin :

Use Terazosin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Terazosin. Talk to your pharmacist if you have questions about this information.
• If you miss a dose of Terazosin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than one dose is missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Terazosin.

Important safety information:

• Terazosin may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Terazosin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Terazosin ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Terazosin may cause a sudden drop in blood pressure after the very first dose. Take you first dose at bedtime. If you get up during the night, sit up slowly, then stand slowly. This will help to reduce your lightheadedness or dizziness. These effects will more likely occur after you have taken the first few doses or if you have increased your dose, but can occur at any time while you are taking the medicine. It can also occur if you stop taking the medicine and restart treatment.
• Terazosin may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel “normal.” Tell your doctor if you develop any new symptoms.
• Terazosin may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
• Terazosin should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Terazosin while you are pregnant. It is not known if Terazosin is found in breast milk. If you are or will be breast-feeding while you use Terazosin , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Terazosin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth; feeling of a whirling motion; headache; lightheadedness; nasal congestion; nausea; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; chest pain; decreased sexual ability; difficulty breathing; easy bleeding or bruising; fainting; painful penile erection; pounding or tightness in the chest; ringing in the ears; swelling of the hands or feet.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

What is/are Hydrochlorothiazide Tablets?

HYDROCHLOROTHIAZIDE is a diuretic. It increases the amount of urine passed, which causes the body to lose salt and water. This medicine is used to treat high blood pressure. It is also reduces the swelling and water retention caused by various medical conditions, such as heart, liver, or kidney disease. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

• diabetes
• gout
• immune system problems, like lupus
• kidney disease or kidney stones
• liver disease
• pancreatitis
• small amount of urine or difficulty passing urine
• an unusual or allergic reaction to hydrochlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Remember that you will need to pass urine frequently after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not stop taking your medicine unless your doctor tells you to.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

• cholestyramine
• colestipol
• digoxin
• dofetilide
• lithium
• medicines for blood pressure
• medicines for diabetes
• medicines that relax muscles for surgery
• other diuretics
• steroid medicines like prednisone or cortisone

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
• chest pain
• fast or irregular heartbeat
• feeling faint or lightheaded, falls
• gout attack
• muscle pain or cramps
• pain or difficulty when passing urine
• pain, tingling, numbness in the hands or feet
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blurred vision
• dry mouth
• headache
• stomach upset

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her.

You may need to be on a special diet while taking this medicine. Ask your doctor.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine may affect your blood sugar level. If you have diabetes, check with your doctor or health care professional before changing the dose of your diabetic medicine.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Protect from light and moisture. Keep container closed tightly. Throw away any unused medicine after the expiration date.

What is/are Hydrochlorothiazide Tablets?

HYDROCHLOROTHIAZIDE is a diuretic. It increases the amount of urine passed, which causes the body to lose salt and water. This medicine is used to treat high blood pressure. It is also reduces the swelling and water retention caused by various medical conditions, such as heart, liver, or kidney disease. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

• diabetes
• gout
• immune system problems, like lupus
• kidney disease or kidney stones
• liver disease
• pancreatitis
• small amount of urine or difficulty passing urine
• an unusual or allergic reaction to hydrochlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Remember that you will need to pass urine frequently after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not stop taking your medicine unless your doctor tells you to.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

• cholestyramine
• colestipol
• digoxin
• dofetilide
• lithium
• medicines for blood pressure
• medicines for diabetes
• medicines that relax muscles for surgery
• other diuretics
• steroid medicines like prednisone or cortisone

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
• chest pain
• fast or irregular heartbeat
• feeling faint or lightheaded, falls
• gout attack
• muscle pain or cramps
• pain or difficulty when passing urine
• pain, tingling, numbness in the hands or feet
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• blurred vision
• dry mouth
• headache
• stomach upset

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her.

You may need to be on a special diet while taking this medicine. Ask your doctor.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine may affect your blood sugar level. If you have diabetes, check with your doctor or health care professional before changing the dose of your diabetic medicine.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not freeze. Protect from light and moisture. Keep container closed tightly. Throw away any unused medicine after the expiration date.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Valsartan is used for:

Treating high blood pressure alone or with other medicines. It is also used for treating heart failure in patients who do not tolerate angiotensin-converting enzyme (ACE) inhibitors.

Valsartan is an angiotensin II receptor blocker. It works by blocking a hormone that tightens blood vessels. This causes blood vessels to relax (dilate), which lowers blood pressure and decreases the workload on the heart.

Do NOT use Valsartan if:

• you are allergic to any ingredient in Valsartan
• you are past your first trimester of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Before using Valsartan :

Some medical conditions may interact with Valsartan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have dehydration or low blood sodium, or kidney or liver problems
• if you have heart failure or you have had a heart attack

Some MEDICINES MAY INTERACT with Valsartan. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Potassium-sparing diuretics (eg, amiloride) and potassium supplements because high blood potassium levels may occur and cause listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, or stopping of the heart when used with Valsartan
• Lithium because its actions and side effects may be increased by Valsartan

This may not be a complete list of all interactions that may occur. Ask your health care provider if Valsartan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Valsartan :

Use Valsartan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Valsartan by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Take Valsartan on a regular schedule to get the most benefit from it.
• If you miss a dose of Valsartan , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Valsartan.

Important safety information:

• Valsartan may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Valsartan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Valsartan may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel “normal.” Tell your doctor if you develop any new symptoms.
• Check with your doctor before you use a salt substitute or a product that has potassium in it.
• Lab tests, including blood pressure monitoring, may be performed while you use Valsartan. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Valsartan should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Do not take Valsartan after the third month of pregnancy. It may cause injury or death to the fetus. If you become pregnant, contact your doctor right away. It is not known if Valsartan is found in breast milk. If you are or will be breast-feeding while you use Valsartan , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Valsartan :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; cough; diarrhea; dizziness; headache; joint pain; nausea; runny nose; sinus inflammation; sore throat; stomach pain; swelling; tiredness; upper respiratory tract infection; viral infection.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decreased urination; fainting; irregular heartbeat; muscle pain; severe or persistent dizziness.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Drug Name

Coumadin (Warfarin)

Drug Uses

Coumadin treats or prevents blood clots that may occur in the veins and lungs. It is also used to reduce the risk of death, recurring heart attack, or blood clotting events (e.g., stroke) after a heart attack.

How Taken Drug

Use Coumadin as directed by your doctor.

Take Coumadin by mouth with or without food.

Do not eat grapefruit or drink grapefruit juice while you use Coumadin.

It is very important to take Coumadin on a regular schedule as prescribed by your doctor. Take Coumadin at the same time each day.

Continue to take Coumadin even if you feel well. Do not miss any doses, unless directed to do so by your doctor.

Ask your health care provider any questions you may have about how to use Coumadin.

Drug Class and Mechanism

Coumadin is an anticoagulant. It works by blocking the formation of ceratin blood clotting factors.

Missed Dose Drug

If you miss a dose of Coumadin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

If you miss a dose of Coumadin, contact your doctor right away. Take the missed dose as soon as possible if you remember on the same day. If you do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Warnings/Precautions

Do not use Coumadin if:

• you are allergic to any ingredient in Coumadin;
• you have bleeding tendencies, bleeding problems (eg, hemophilia), severe or uncontrolled high blood pressure, certain blood problems (eg, low white blood cell or platelet levels), or leukemia;
• you have active serious bleeding, bleeding in the brain, certain blood vessel problems (eg, aneurysm, dissecting aorta), or inflammation or infection of the heart;
• you have active ulcer or bleeding of the stomach or bowel, urinary tract, genitals, or respiratory tract;
• you have recently had or will be having eye, brain, or spinal cord surgery;
• spinal puncture;
• spinal anesthesia;
• or any type of major surgery;
• you are pregnant or may become pregnant;
• you are unable to have routine blood clotting tests;
• you are unable to follow your doctor’s instructions properly and do not have someone to help you take your medicine;
• you are taking mifepristone, streptokinase, or urokinase.

Contact your doctor or health care provider right away if any of these apply to you.

Important:

Tell your doctor or dentist that you take Coumadin before you receive any medical or dental care, emergency care, or surgery.

Do not drink alcohol while you are taking Coumadin; it may increase the risk of Coumadin’s side effects.

Do not change you activity level or weight without checking with your doctor; the risk of Coumadin side effects may be increased.

Do not eat cranberry products or drink cranberry juice while you are taking Coumadin. Tell your doctor if these products are already part of your diet.

Elevated body temperature may increase the effect of Coumadin. Be careful to avoid becoming overheated, especially during hot weather.

Coumadin decreases blood clotting. Use caution while doing activities such as brushing your teeth, flossing, or shaving.

Avoid activities that may cause bruising or injury. Seek immediate medical attention if you fall or injure yourself. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

Do not take aspirin while you take Coumadin unless your doctor tells you to. If you already take aspirin for a heart or other condition, talk with your doctor about whether or not you should continue to take it with Coumadin.

Tell your doctor if you will be traveling or if you will be confined to a bed or chair for a long period of time (eg, car or airplane ride). This may increase your risk of developing a blood clot.

If therapy with Coumadin is stopped, the blood thinning effects may last for 2 to 5 days after you stop taking it. Discuss any questions or concerns with your doctor. Do not suddenly stop taking Coumadin without checking with your doctor.

Lab tests, including certain blood clotting tests (eg, PT, INR), may be performed while you use Coumadin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Coumadin with caution in Asian patients; they may be more sensitive to its effects, especially bleeding.

Use Coumadin with caution in the elderly; they may be more sensitive to its effects, especially bleeding.

Coumadin should be used with extreme caution in children; safety and effectiveness in children have not been confirmed. Children may need more frequent lab tests if they use Coumadin.

Pregnancy and breast-feeding: Do not use Coumadin if you are pregnant. It has been shown to cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Coumadin is found in breast milk. If you are or will be breast-feeding while you use Coumadin, check with your doctor. Discuss any possible risks to your baby.

Possible Side Effects

Seek medical attention right away if any of these severe side effects occur:

• severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
• back, side, muscle, joint, or stomach pain;
• black, tarry, or bloody stools;
• blood in the urine (pink or brown urine);
• bloody or coffee ground-like vomit;
• chest pain;
• decreased urination;
• dizziness;
• fainting;
• fever;
• numbness or tingling;
• pain, unusual color, or temperature change in any area of the body;
• pale skin;
• purple, dark, or painful toes;
• shortness of breath;
• skin sores or ulcers;
• stroke symptoms (eg, confusion, slurred speech, vision problems, one-sided weakness);
• sudden severe pain in your legs, feet, or toes;
• trouble swallowing; unexplained swelling; unusual bruising or bleeding (eg, nosebleed, unusual bleeding from gums, increased bleeding from cuts, increased menstrual or vaginal bleeding, coughing up blood);
• unusual headache or weakness;
• unusual pain, swelling, or discomfort; wounds or sores that do not heal properly; yellowing of the skin or eyes.

More Information

Coumadin is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Clorpres is used for:

Treating high blood pressure. It may also be used for other conditions as determined by your doctor.

Clorpres is a combination alpha agonist and diuretic. The alpha agonist works by relaxing blood vessels and decreasing heart rate. The diuretic works by increasing elimination of sodium and water.

Do NOT use Clorpres if:

you are allergic to any ingredient in Clorpres , thiazides (eg, hydrochlorothiazide) or related diuretics, or to sulfonamide medicines (eg, sulfamethoxazole) you are unable to urinate

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clorpres :

Some medical conditions may interact with this medicine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have a blood vessel disease affecting the brain, heart or blood vessel problems, or you have had a stroke or recent heart attack if you have gout, liver disease, low blood levels of potassium or sodium, kidney problems, the blood disease porphyria, lupus, or if you are vomiting if you have a history of allergy or bronchial asthma if you will be in a hot environment for long periods of time if you are scheduled for surgery

Some MEDICINES MAY INTERACT with Clorpres . Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol) or calcium channel blockers (eg, verapamil) because a severe decrease in heart rate or an increase or decrease in blood pressure may occur Tricyclic antidepressants (eg, amitriptyline) because they may decrease Clorpres ’s effectiveness Barbiturates (eg, phenobarbital), corticosteroids (eg, cortisone), or narcotics (eg, codeine) because they may increase the risk of Clorpres ’s side effects Diazoxide, digitalis glycosides (eg, digoxin), ketanserin, lithium, tubocurarine, or other medicines for high blood pressure because their actions and the risk of their side effects may be increased by Clorpres Insulin, norepinephrine, or oral diabetes medicines (eg, glipizide) because their effectiveness may be decreased by Clorpres

This may not be a complete list of all interactions that may occur. Ask your health care provider if Clorpres may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clorpres :

Use Clorpres as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Clorpres by mouth with or without food.

Take Clorpres on a regular schedule to get the most benefit from it.

Continue to use Clorpres even if you feel well. Do not miss any doses.

Clorpres may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.

If you miss a dose of Clorpres , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you miss 2 or more doses in a row, contact your doctor.

Ask your health care provider any questions you may have about how to use Clorpres .

Important safety information:

Clorpres may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Clorpres with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Clorpres ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

Clorpres may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel “normal.” Tell your doctor if you develop any new symptoms.

If you experience dry mouth, use sugarless candy or gum, or melt bits of ice in your mouth to help keep your mouth moist.

Clorpres may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.

Clorpres may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Clorpres . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Tell your doctor or dentist that you take Clorpres before you receive any medical or dental care, emergency care, or surgery.

Diabetes patients – Clorpres may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Lab tests, including blood pressure and blood electrolyte levels, may be performed while you use Clorpres . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Clorpres with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness.

Clorpres should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. Also, CHILDREN who are sick and vomiting may be more sensitive to developing withdrawal symptoms.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Clorpres while you are pregnant. Clorpres is found in breast milk. Do not breast-feed while using Clorpres .

If you stop taking Clorpres suddenly, you may have WITHDRAWAL symptoms. These may include nervousness, agitation, headache, tremor, and rapid increase in blood pressure.

Possible side effects of Clorpres :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; confusion; dark urine; decreased urination; depression; fast, slow, or irregular heartbeat; fever, chills, or sore throat; hallucinations; inability to have sex; increased thirst; joint pain (gout); muscle pain or cramps; nausea; numbness or tingling of the skin; pounding in the chest; rapid breathing; red, swollen, blistered, or peeling skin; restlessness; severe or persistent drowsiness or dry mouth; sluggishness; unusual bruising or bleeding; unusual tiredness or weakness; vision changes; vomiting; weakness; yellowing of the skin or eyes.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Drug Name

Cardura (Doxazosin)

Drug Uses

Cardura is used for the control of elevated blood pressure (hypertension) and for benign prostatic hyperplasia (noncancerous enlargement of the prostate gland).

How Taken

Cardura should be taken at doses, specifically directed by your physician. This medication can be taken with or without food. Cardura should be taken at the same time each day to maintain proper blood levels. Do not take Cardura within two hours of taking an antacid. If stopped, you must taper the dose.

Drug Class and Mechanism

Cardura is an inhibitor of alpha 1 adrenergic nervous system. It is in a class of drugs, referred to as alpha blockers that includes alfusosin (Uroxatral), terazosin (Hytrin), tamsulosin (Flomax), and prazosin (Minipress). Elevated blood pressure (hypertension) is lowered as the action of these nerves, which promote constriction of blood vessels, is blocked.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. If you are taking 1 dose daily and do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store in a dry place at 30 degrees C (86 F).

Warnings/Precautions

Do not take this medicine if you have had an allergic reaction to it, or are allergic to any ingredient in this product, or to any similar medicine. Before you hve any medical or dental treatments, energency care, or sergery (especially cataract surgery), tell the doctor or dentist that you are using this medicine.

This medicine may cause drowsiness, dizziness, or lightheadedness. Take the first dose at bedtime. If you get up during the night, sit up and stand up slowly. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.

This medicine can cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.

For women: if you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. It is unknown if this medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible Side Effects

Side effects that may occur while taking this medicine include

• dizziness,
• headache,
• nausea,
• drowsiness,
• lack of energy,
• dry mouth, or nasal congestion.

If they continue or are bothersome, check with your doctor. Check with your doctor as soon as possible if you experience pounding heartbeat, puffiness in hands or feet, blurred vision, bloody urine, or if you are unable to control your urination.

Contact your doctor immediately if you experience difficulty breathing; tightness of chest; swelling of eyelids, face or lips; or if you develop a rash or hives, tell your doctor immediately.

If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

More Information

Do not share the medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extendedperiod of time, obtain refills before your supply runs out.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

Drug Name

Calan (Verapamil)

Drug Uses

This drug is a calcium channel blocker. Calcium is involved in blood vessel contraction and in controlling the electrical impulses within the heart. By blocking calcium, calan relaxes and widens blood vessels and can normalize heartbeats. Calan is used to treat chest pain (angina), high blood pressure or irregular heartbeats. Ask your doctor or pharmacist about possible problems related to use of short-acting calcium channel blockers.

How Taken

This medication should be swallowed whole with a full glass of water unless your doctor directs you otherwise. This medication must be taken as directed to prevent chest pain. It is not effective if taken only when chest pain occurs. Do not stop taking this medication suddenly without your doctor’s permission. Chest pain can occur if the medication is stopped too fast. Your dose may need to be gradually decreased.

Drug Class and Mechanism

Calan belongs to a class of medications, called calcium channel blockers. These medications block the movement of calcium into the muscle cells of the coronary arteries (the arteries supplying the heart) as well as the other arteries of the body. Since calcium is what triggers contraction of muscles, blocking entry of calcium relaxes the arterial muscles.

This relaxation allows the arteries to become larger so that more blood can flow through them. Thus, calan is useful in treating and preventing chest pain (angina) resulting from spasm (contraction) of the coronary arteries that reduces the flow of blood to the heart. Relaxing the muscles lining the arteries in the rest of the body lowers blood pressure and thereby reduces the pressure against which the heart must pump blood.

As a result, the heart works less and requires less oxygen-carrying blood. This allows the heart to work with the reduced flow of blood caused by coronary artery disease and prevents angina (which occurs whenever the flow of blood to the heart is inadequate). Calan also decreases the conduction of electrical impulses through the heart that control the coordination of contraction. As a result, the rate of contraction slows.

Missed Dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not “double-up” the dose to catch up.

Storage

Store at room temperature away from sunlight and moisture.

Warnings/Precautions

Before using this drug, tell your doctor your medical history, including:

• allergies (especially drug allergies),
• heart problems (e.g., heart rhythm disturbances, heart failure),
• liver or kidney disease,
• very low blood pressure, muscular dystrophy, brain tumors (cancer).

Before heart surgery, tell your doctor you use this medicine. Calan prolongs and intensifies the effects of alcohol in your system. Avoid (or very carefully limit) alcoholic beverages while using this medication. Caution is advised when this drug is used in the elderly.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk and a decision should be made whether to stop the drug or avoid breast-feeding. Consult your doctor before breast-feeding.

Possible Side Effects

This drug may cause dizziness and lightheadedness especially during the first few days. Avoid activities requiring alertness. When you sit or lie down for a while, get up slowly to allow your body to adjust and minimize dizziness.

You may also experience weakness, fatigue, nausea, muscle cramps, headache, flushing or constipation. These effects should disappear as your body adjusts to the medication. Inform your doctor if they become bothersome.

Notify your doctor immediately if you develop:

• breathing difficulties,
• swelling of the hands or feet,
• irregular heartbeat,
• fever,
• stomach/abdominal pain,
• yellowing eyes and skin,
• dark urine.

If you notice other effects not listed above, contact your doctor or pharmacist.

More Information

Laboratory tests (e.g., liver function tests) should be performed periodically to monitor for side effects. Do not share this medication with others.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.